<scp>CircSMARCA5</scp> functions as a potential biomarker for clinicopathology and therapy in solid tumors: A systematic review and meta‐analysis

Circular RNAs (circRNAs) have been implicated in cancer proliferation, migration, and invasion. Among various circRNAs, circSMARAC5 attracted our great attention. The research aimed at broadening the knowledge on circSMARCA5 exploring its function clinicopathology therapy solid tumors. incorporated was explored via Web of Science, PubMed, Embase, Cochrane Library, consisting 1048 patients. This study calculated using STATA 12.0 Review Manager 5.3 software. Clinicopathological characteristics therapeutic targets were analyzed pooled odd ratios (ORs) with 95% confidence intervals (CIs). And ceRNA network constructed Cytoscape 3.9.0. Eventually, there eight studies included conducting clinicopathological four literature used targets. Patients low expression closely associated gender (OR = 1.367, CI 1.003–1.862, p .048) pathological differentiation 1.627, 1.130–2.343, .009). these modulating axes, most commonly microRNA miR-432. In near future, may be a promising diagnostic biomarker new target.